OpenAI Podcast

Technology

About

Hosted by Andrew Mayne, The OpenAI Podcast features conversations with the people building with and working at OpenAI. Topics range from how new features are developed to what users are doing with the technology. It’s a practical look at how AI is made and where it’s going, told by the people closest to the work. Hosted on Acast. See acast.com/privacy for more information.

Episodes

  • Episode 18 - Why AI needs a new kind of supercomputer network

    Mark Handley and Greg Steinbrecher explain OpenAI's new supercomputer network architecture designed for training large AI models. They detail the Multipath Reliable Connection protocol, developed with industry partners, and discuss its rol…

  • Episode 17 - What happens now that AI is good at math?

    OpenAI researchers Sébastien Bubeck and Ernest Ryu discuss the rapid progress of AI in mathematics, how AI like ChatGPT can solve complex problems and even assist in research, and the potential impact on the future of AGI.

  • Episode 16 - Building AI for Life Sciences

    Joy Jiao and Yunyun Wang discuss OpenAI's work in life sciences AI, covering applications in research, drug discovery, and autonomous labs, alongside crucial considerations for responsible deployment and biosecurity.

  • Episode 15 - Inside the Model Spec

    In this episode of the OpenAI Podcast, host Andrew Mayne and researcher Jason Wolfe delve into the Model Spec, a public framework that guides AI model behavior. They explore its practical implementation, how conflicts are managed, and the…

  • Episode 14 - Building AI for better healthcare

    OpenAI

  • Episode 13 - The Thinking Behind Ads in ChatGPT

    Asad Awan from OpenAI explains the company's approach to advertising within ChatGPT, detailing how ads will be kept separate from model responses, user conversations will remain private from advertisers, and users will have control over th…

  • Episode 12 - State of the AI Industry

    OpenAI CFO Sarah Friar and Khosla Ventures founder Vinod Khosla discuss the primary challenges in the AI industry, focusing on meeting demand and ensuring broad benefit. They also explore the drivers behind compute investments and differen…

  • Episode 11- Shaping Model Behavior in GPT-5.1

    Researchers Christina Kim and Laurentia Romaniuk discuss how OpenAI developed GPT-5.1 to balance intelligence and emotional quotient (EQ), focusing on aspects like model personality, steerability, and the role of memory.

  • Episode 10 - How AI Is Accelerating Scientific Discovery Today and What's Ahead

    Kevin Weil and Alex Lupsasca from OpenAI discuss the early impact of AI, specifically GPT-5, on scientific research. They cover its capabilities in literature analysis, calculation, and experiment design, and speculate on the future accele…

  • Episode 9 - ChatGPT Atlas and the next era of web browsing

    OpenAI

  • Episode 8 - OpenAI x Broadcom and the future of compute

    OpenAI's Sam Altman and Greg Brockman discuss a new partnership with Broadcom's Hock Tan and Charlie Kawwas, covering custom silicon, AI infrastructure scale, and the crucial role of compute innovation in achieving AGI.

  • Episode 7 - Live from DevDay

    The OpenAI Podcast's first live episode features host Andrew Mayne interviewing founders from Cursor, Abridge, SchoolAI, and Jam.dev. They discuss how AI is being applied to transform industries including healthcare, education, coding, and…

  • Episode 6 - The future of coding with AI

    OpenAI co-founder Greg Brockman and Codex engineering lead Thibault Sottiaux explore the evolution of AI in coding, discussing its potential as a collaborative partner. They cover topics like agentic coding, code review advancements, and t…

  • Episode 5 - Defining AGI and the road ahead

    OpenAI Chief Scientist Jakub Pachocki and researcher Szymon Sidor discuss the progress towards Artificial General Intelligence (AGI), exploring breakthroughs in AI reasoning, the potential for automating scientific discovery, and the futur…

  • Episode 4 - How AI is transforming education

    OpenAI's Head of Education, Leah Belsky, discusses AI's role in transforming education, from personalized tutoring to new teaching models. College students Yabsera and Alaap share their experiences learning in the AI era, covering topics l…

  • Episode 3 - Jobs, growth, and the AI economy

    OpenAI COO Brad Lightcap and Chief Economist Ronnie Chatterji discuss the AI economy with Andrew Mayne, covering AI's impact on various sectors including software, science, small business, and education, as well as its effects on jobs and…

  • Episode 2 - Inside ChatGPT, AI assistants, and building at OpenAI

    OpenAI leaders Nick Turley and Mark Chen discuss the surprising success of ChatGPT, the meaning of AI reasoning, and the future of AI assistants, including coding and multimodal capabilities.

  • Episode 1 - Sam Altman on AGI, GPT-5, and what’s next

    Sam Altman discusses AGI, GPT-5, Project Stargate, research workflows, and AI's impact on parenting with host Andrew Mayne on the inaugural OpenAI Podcast. Topics include model naming, user privacy, and the future of AI devices.

  • The OpenAI Podcast Is Coming

    The official OpenAI Podcast is announced as coming soon. The podcast is hosted on Acast, and further information regarding privacy can be found at acast.com/privacy.