Healthy Dialogue
Health, Fitness & Longevity
About
Go beyond the latest discoveries with nuanced, in-depth conversations in Healthy Dialogue, a podcast from the JAMA Network. Host and JAMA Senior Editor, Derek C. Angus, MD, MPH, sits down with the world's leading experts to explore the most pressing issues in health and health care.
Episodes
- AI Scribes Are Here, but Is Health Care Ready?
Host Derek Angus, MD, MPH, and Dr. Vincent Liu discuss the fast technological changes in health care due to ambient AI scribes, examining the readiness of the industry for this technology.
- Rethinking the Autism "Epidemic": What's Driving the Rise in Diagnosis
Jeremy Veenstra-VanderWeele and Dost Öngür explore factors contributing to the increase in autism diagnoses. They cover the history of autism spectrum disorder, the influence of genetics and environmental factors, and the significance of e…
- Introducing Healthy Dialogue
Healthy Dialogue, from the JAMA Network and hosted by Derek C. Angus, MD, MPH, offers in-depth conversations with leading experts on important health and health care topics.
- From the JAMA Network: JAMA Research of the Year With Editor in Chief Kirsten Bibbins-Domingo
Kirsten Bibbins-Domingo, Editor in Chief of JAMA, and Jennifer Abbasi, Medical News Director, talk about the journal's first collection of Research of the Year.
- The Sequential Organ Failure Assessment (SOFA)-2 Score
The SOFA-2 score, validated in over 3 million ICU patients, shows strong predictive validity for ICU mortality by incorporating current organ support treatments. Mervyn Singer, MD, and Christopher W. Seymour, MD, MSc, discuss its developme…
- From the JAMA Network: Acetaminophen Use in Pregnancy and Risk of Autism
Epidemiologist Brian Lee, PhD, discusses his study on acetaminophen use during pregnancy and children's risk of autism and other neurodevelopmental disorders in this interview with JAMA Deputy Editor Linda Brubaker, MD. Related Content: Ac…
- From the JAMA Network: AI-Based Analysis for Parkinsonism
Delaying diagnosis of parkinsonism can mean delaying care. In a study recently published in JAMA Neurology, David Vaillancourt, PhD, and colleagues tested the ability of an AI model to differentiate between Parkinson disease and other neur…
- Treatment of Complicated Staphylococcus aureus Bacteremia
Dalbavancin, a long-acting IV lipoglycopeptide, may be an option for the treatment of complicated Staphylococcus aureus bacteremia without requiring long-term IV access. Author Thomas L. Holland, MD, MSc, from Duke University School of Med…
- From the JAMA Network: Incidence and Nature of Antidepressant Discontinuation Symptoms
Interview with Sameer Jauhar, PhD, author of Incidence and Nature of Antidepressant Discontinuation Symptoms: A Systematic Review and Meta-Analysis. Hosted by John Torous, MD. Related Content: Incidence and Nature of Antidepressant Discont…
- From the JAMA Network: GLP-1 Receptor Agonists in Idiopathic Intracranial Hypertension
Interview with Dennis J. Rivet II, MD, author of GLP-1 Receptor Agonists in Idiopathic Intracranial Hypertension. Hosted by Cynthia E. Armand, MD. Related Content: GLP-1 Receptor Agonists in Idiopathic Intracranial Hypertension
- Life Support and Outcomes in Patients Admitted to Intensive Care Units
Nationwide data are unavailable regarding changes in intensive care unit (ICU) outcomes over the past 10 years, limiting understanding of practice changes. Authors Emily Moin, MD, MBE, and Scott D. Halpern, MD, PhD, MBE, of the University…
- Increases in Invasive Group A Streptococcal Infections
The incidence of invasive group A streptococcal infections has risen in the US. Similar observations have been reported in other parts of the world. Authors Joshua Osowicki, MBBS, PhD, of Murdoch Children's Research Institute and Theresa L…
- Preventive Health Care Among Adults Eligible for Lung Cancer Screening
Less than 20% of patients eligible for lung cancer screening get screened in the US. A recent study examined whether adults eligible for lung cancer screening engage in screening for other types of cancer. Coauthor Chi-Fu Jeffrey Yang, MD,…
- Cardiac Arrests During Long-Distance Running: What's Changed?
Despite increased participation in US long-distance running races, cardiac arrest incidence remains stable. Authors Jonathan Kim, MD, MSc, of Emory University, and Aaron Baggish, MD, of the University of Lausanne Switzerland, discuss the R…
- Inhaled Sedation With Sevoflurane for Acute Respiratory Distress Syndrome (ARDS)
ARDS, which is characterized by hypoxemic respiratory failure and inflammatory injury to the lungs, has a mortality rate of 30% to 40%. Balasubramanian Venkatesh, MD, of the George Institute for Global Health joins JAMA Deputy Editor Krist…
- New FDA Pulse Oximetry Guidance: Strengths and Weaknesses
The US Food and Drug Administration (FDA) issued new draft regulatory guidance for pulse oximeters related to skin pigment. The guidance is a step forward but it may have unintended consequences. Authors Michael Lipnick, MD, and Philip Bic…
- Combining CAC Score With Treatment on Plaque Progression in Familial Coronary Artery Disease
The CAUGHT-CAD randomized clinical trial sought to determine whether a CAC score-informed strategy could slow the progression of coronary plaque volume. Author Thomas H. Marwick of the Baker Heart & Diabetes Institute joins JAMA Associate…
- Evaluating Treatments for Amyotrophic Lateral Sclerosis
The HEALEY ALS platform is an innovative first attempt at platform trials in ALS, looking to slow ALS disease progression. Author Sabrina Paganoni, MD, PhD, of Massachusetts General Hospital and Harvard Medical School, discusses results of…
- US Health Care Spending by Health Condition and County—What Drives Variation?
Understanding health conditions with the most spending and variation across locations and over time is important for identifying trends, inequalities, and strategies for lowering health spending. Joseph Dieleman, PhD, of the University of…
- Supporting Children and Families in an Era With Abortion Restrictions
Two recent studies published in JAMA provide evidence about the effects of state-level abortion restrictions on birth rates and infant mortality. Author Alyssa Bilinski, PhD, MSc, of Brown University School of Public Health joins JAMA Depu…
- Evaluating Comprehensive Models–Challenges and Innovations in Dementia Care
Contemporary models of dementia care are multidisciplinary and aim to bridge medical and social services. Julie P. W. Bynum, MD, MPH, of the University of Michigan speaks with JAMA Deputy Editor Christopher C. Muth, MD, about 2 trials—the…
- Intra-Arterial Thrombolytics Following Thrombectomy for Ischemic Stroke
Two new trials published in JAMA evaluate the efficacy of periprocedural intra-arterial thrombolytics after successful endovascular thrombectomy for patients with acute ischemic stroke. Diederik Dippel, MD, PhD, of Erasmus University Medic…
- Impact of Private Equity Acquisition on Patient Care Experience in US Hospitals
Private equity acquisitions of health care facilities have rapidly increased over the past decade. However, little is known about the effects of these acquisitions on patient experience. Author Rishi K. Wadhera, MD, MPP, MPhil, of Harvard…
- Asthma Endotypes Based on Nasal Epithelial Biopsies in School-Aged Youth
Certain CD4+ T-cell subtypes play a role in asthma. Characterizing asthma endotypes in diverse groups is important to help develop effective therapies for youth with asthma. Author Juan C. Celedon, MD, DrPH, University of Pittsburgh, Depar…
- Dental Benefits and Medicare Advantage Plans
Most Medicare Advantage (MA) plans offer dental care coverage as a supplemental benefit. However,few beneficiaries are enrolled in an MA plan that provides comprehensive dental benefits. Lisa Simon, MD, DMD, discusses this and more with JA…
- 2024 Update on Long COVID Classification and Symptom List
Long COVID is now defined as a heterogeneous, infection-associated chronic condition present for at least 3 months after SARS-CoV-2 infection. Author Leora Horwitz, MD, MHS, of NYU Grossman School of Medicine joins JAMA Executive Editor Gr…
- Camrelizumab vs Placebo With Chemotherapy as Neoadjuvant Treatment in Triple-Negative Breast Cancer
Triple-negative breast cancer accounts for around 15% of breast cancers. Zhi-Ming Shao, MD, of Fudon University, joins JAMA Oncology Editor in Chief and JAMA Deputy Editor Nora Disis, MD, to discuss "Camrelizumab vs Placebo in Combination…
- HIV Treatment and Prevention: Updated Recommendations
New antiretroviral drugs and formulations continue to become available for the prevention and management of HIV infection. Author Rajesh T. Gandhi, MD, joins JAMA Deputy Editor Preeti Malani, MD, MSJ, to discuss these new approaches for HI…
- The Impacts of Severe Maternal Morbidity
A new JAMA study examines the association between severe maternal morbidity in a first birth and the probability of a subsequent birth. Authors Neda Razaz, PhD, and Eleni Tsamantioti, MD, MMedSc, both from the Karolinska Institute in Swede…
- Zerlasiran, a Small-Interfering RNA That Targets Lipoprotein(a)
Elevated lipoprotein(a) levels increase the risk of atherosclerotic cardiovascular disease (ASCVD) and aortic stenosis. Cleveland Clinic's Steven E. Nissen, MD, speaks with JAMA Executive Editor Gregory Curfman, MD, about how zerlasiran pr…
- Intratracheal Budesonide for Extremely Preterm Infants
Preterm birth is the greatest cause of neonatal mortality and morbidity, with infants born extremely preterm at highest risk. Author Brett J. Manley, PhD, the Royal Women's Hospital, Melbourne, Australia, discusses a new study of the effec…
- Digital Health Behavior Intervention to Prevent Childhood Obesity
Preventing obesity in early childhood is challenging for clinicians and families. Authors Eliana M. Perrin, MD, MPH, of Johns Hopkins University, and William J. Heerman, MD, MPH, of Vanderbilt University, join JAMA Deputy Editor Tracy Lieu…
- Drug Shortages After Supply Chain Issues in the US vs Canada
A new study published in JAMA found that drug-related supply chain issue reports were 40% less likely to result in meaningful drug shortages in Canada compared with the US. Authors Kate Suda, PharmD, MS, of University of Pittsburgh School…
- Advanced Birth Centers Raise Safety Concerns for Obstetric Care
In the US, childbirth typically occurs in hospitals or accredited birth centers. President of the American College of Obstetricians and Gynecologists Stella Marie Dantas, MD, speaks with JAMA Deputy Editor Linda Brubaker, MD, MS, about new…
- Declaration of Helsinki Addresses New Ethical Challenges
The Declaration of Helsinki originated in 1964, developed by the World Medical Association (WMA). Process Chair Jack S. Resneck Jr, MD, discusses the 2024 updates to the Declaration of Helsinki with JAMA Editor in Chief Kirsten Bibbins-Dom…
- JAMA Critical Care Research at ESICM Congress 2024
Transfusion strategy for patients with acute brain injury, telehealth care, acute kidney injury after cardiac surgery, and weaning ventilatory support are the topics of 4 trials published in JAMA and presented at the 2024 European Society…
- Fecal Immunochemical Test (FIT) and Helicobacter pylori Stool Antigen Co-Testing for Gastric Cancer
Gastric cancer is a leading cause of cancer death globally. Chronic H pylori infection is the primary cause of gastric cancer, responsible for at least 80% of the new cases. Constanza Camargo, PhD, of the National Cancer Institute joins JA…
- Preventing Fever in Patients With Acute Vascular Brain Injury
Fever is associated with worse outcomes in patients with stroke, but whether preventing fever improves outcomes is unclear. David M. Greer, MD, MA, speaks with JAMA Associate Editor Jeffrey L. Saver, MD, about fever prevention in patients…
- The Discovery of Glucagon-Like Peptide 1 (GLP-1)
The 2024 Lasker–DeBakey Clinical Medical Research Award has been presented for the discovery of GLP-1 and its application to the treatment of obesity. Lasker winner Svetlana Mojsov, PhD, discusses her role in this innovative discovery and…
- Improving Access to Palliative Care for Patients With Cancer
Palliative care is an essential component to high-quality care for patients with cancer. How can access to palliative care be expanded? Eduardo Bruera, MD, from MD Anderson Cancer Center speaks with JAMA Editor in Chief Kirsten Bibbins-Dom…
- Balloon Angioplasty for Intracranial Atherosclerotic Stenosis
A new trial assessed whether balloon angioplasty plus aggressive medical management was superior to aggressive medical management alone for patients with symptomatic intracranial atherosclerotic stenosis. Author Zhongrong Miao, MD, PhD, fr…
- Concerning Mortality Rate Trends in the US
The abating COVID-19 pandemic brings attention to rising mortality rates from non-COVID causes in the US, a trend that predates the COVID-19 pandemic. Viewpoint author Steven H. Woolf, MD, MPH, discusses this and more with JAMA Executive E…
- Menopause-Associated Vasomotor Symptom Treatment With Elinzanetant
Nonhormonal treatments for menopausal vasomotor symptoms may benefit symptomatic patients who cannot take or prefer to avoid systemic hormones. Author JoAnn V. Pinkerton, MD, MSCP, discusses the efficacy and safety of elinzanetant for the…
- Long COVID in Children
To address the need to characterize long COVID in children and adolescents, the National Institutes of Health funded a pediatric program in the Researching COVID to Enhance Recovery (RECOVER) Initiative. Editorialist Suchitra Rao, MBBS, MS…
- Uterus Transplant: Innovation and Considerations
A new study looks at uterus transplant to determine if it is safe, feasible, and results in births of healthy infants. Editorialist Emily Jungheim, MD, MSCI, Northwestern University, discusses this innovative treatment with JAMA Deputy Edi…
- A Vaping Cessation Text Message Program for Adolescents
Ten percent of US adolescents use e-cigarettes, and many want to quit. However, evidence on the effectiveness of vaping cessation interventions is lacking. Amanda L. Graham, PhD, of the Truth Initiative discusses with JAMA Senior Editor Tr…
- Diagnostic Accuracy of an Integrated AI Ultrasound Tool for Gestational Age Estimation
Gestational age estimation is foundational for obstetric care. In resource-limited settings, an integrated AI tool allows novice users to improve gestational age estimates. Author Jeffrey Stringer, MD, University of North Carolina, joins J…
- Alzheimer Disease Blood Biomarkers
Biomarkers for Alzheimer disease (AD) provide insight into disease processes and may aid clinical diagnosis for individuals with cognitive impairment. Author Stephen Salloway, MD, MS, of Brown University joins JAMA Deputy Editor Christophe…
- Risankizumab for Ulcerative Colitis
Ulcerative colitis can significantly decrease quality of life. A third of patients have persistent symptoms with tumor necrosis factor inhibitors and nearly 1 in 5 patients will be hospitalized within 5 years of diagnosis. Author Gilaad G.…
- Influence of Endometriosis Typology on Ovarian Cancer Risk
What are the ovarian cancer risks associated with endometriosis subtypes? Author Karen C. Schliep, PhD, MSPH, of the University of Utah joins JAMA Deputy Editor Linda Brubaker, MD, MS, to discuss Endometriosis Typology and Ovarian Cancer R…