Core IM | Internal Medicine Podcast
Health, Fitness & Longevity
About
Core Internal Medicine via following series:5 Pearls || Clinically relevant pearls Mind the Gap || Why do we do what we do?Gray Matters || Management ReasoningHoofbeats || Dissecting clinical reasoningAt the Bedside || Explore everyday challenges
Episodes
- #207 Is There a Doctor on Board? In-Flight Emergencies
We start with a gripping story of seizures and use it as a jumping-off point to unpack practical pearls for in-flight emergencies. Along the way: what’s actually in the emergency medical kit, when planes divert, how ground medical support…
- #206 Eosinophilia: 5 Pearls Segment
Can you distinguish benign eosinophilia from a sign of serious disease, and know exactly when to act at the bedside? In this high-yield episode, test your clinical reasoning as we tackle: When eosinophilia becomes dangerous and why it matt…
- #205 Nutrition Studies, Coffee and the CRAVE Trial: Beyond Journal Club with the NEJM Group
Is coffee helping or harming our patients’ hearts? In this Beyond Journal Club, we unpack the CRAVE trial and use it as a lens to answer a bigger question: How should clinicians interpret nutrition research, especially when it feels incons…
- #204 Diabetic Foot Infections & Osteomyelitis: 5 Pearls Segment
Why can these infections be tricky? How to diagnose osteomyelitis at the bedside? Do we always need IV vs oral antibiotics? And the best for last: Simple, practical wound care strategies for medical students, residents, and clinicians who…
- #203 POCUS for AKI & Dialysis | Real Cases That Changed Management
A dialysis patient with a chronic cough: is it COPD, or are they still volume overloaded? A patient with AKI and hyperkalemia says they’re still peeing — does that rule out post-obstructive AKI? A patient arrives in the ED with uremic symp…
- #202 Dementia Part 2: Gray Matters Segment
Most clinicians see dementia medications on the med rec, but many of us aren’t sure how much they actually help . In this episode we break down donepezil, memantine, and the new anti-amyloid drugs, and when to stop them. • Do cholinesteras…
- #201: Dementia Part 1: Gray Matters Segment
Cognitive decline is tough for all parties. What are the high-yield questions to ask? What should you add to your one-liner? When do you stop using MOCA and try to clearly describe their functional status? Do all patients with cognitive de…
- #200: Insulin and QWINT-1 Trial in T2DM: Beyond Journal Club Segment with NEJM Group
From metformin to basal insulin to overlooked older medications, this episode reviews the T2D medication toolkit clinicians use every day. We then dive into new evidence on once-weekly insulin to help you individualize therapy while reduci…
- #199 Privacy & Confidentiality: At the Bedside Segment
Is patient confidentiality absolute or conditional? When does protecting privacy put others at risk? Can you follow a former patient in the EHR for learning? Should you post a compelling case online even if it’s “de-identified”? And when d…
- #198 Microskills for Change That are Big Enough to Matter, Small Enough to Win
Baby alligators - those betrayals of purpose , or, death by a thousand paper cuts ! Check out our latest episode, where Dr. Eileen Barrett walks us through how to tackle baby alligators with: Regulated curiosity Strategic empathy Small, we…
- #197 Hypercoagulability Part 2: 5 Pearls Segment
Gray zones of VTE management! How to approach anticoagulation duration in unprovoked, provoked-irreversible, and provoked-reversible clots? When dose-reduced DOACs make sense for long-term secondary prevention? What truly constitutes DOAC…
- #196 Stories of Courage and Career Development with Horn Award
We hope these stories resonate with anyone who has felt pulled between professional purpose and personal life, and remind you that you’re not alone in wanting both. 🔹 Sponsor: Oakstone CME Use the code "CORE30" for 30% off: https://www.co…
- #195 Antibiotic Duration & BALANCE Trial: Beyond Journal Club with NEJM Group
Antibiotic duration for bacteremia is something most of us learned by habit, not by trial data. In this episode, we walk through the BALANCE trial and use it as a lens to revisit how 1) host, 2) organism, and 3) source should guide treatme…
- #194: Severe Hypertriglyceridemia: 5 Pearls Segment
How quickly can triglycerides rise? At what threshold are patients at risk of pancreatitis or cardiovascular adverse outcomes? What do you have to rule out? How do you counsel on lifestyle changes? Which medications do you start with why a…
- #193 Venous Congestion & VEXUS Interview with Dr. Ross Prager
Why is venous congestion not the same as volume overload? How can looking at IVC as well as doppler on the hepatic vein, portal vein, and/or intrarenal vein help? Can venous congestion explain someone's delirium? Or be at play in septic sh…
- #192 Debate on First-Line Medications for Diabetes
SGLT-2i vs. GLP-1? vs Metformin? How do you balance the cost and coverage of first-line options like metformin, SGLT-2, and GLP-1s? How do you choose between SGLT-2 and GLP-1s for comorbidities like CAD or CKD? And how do you weigh their s…
- #191 Hepatorenal Syndrome Part 2 on Management: 5 Pearls Segment
What really works when treating HRS? Vasoconstrictors like terlipressin vs. norepinephrine vs. midodrine: how do we decide which to use? Do you give albumin? When do you give Lasix or another diuretic? When is the better choice transplant,…
- #190: Hepatorenal Syndrome Part 1: 5 Pearls Segment
HRS-AKI vs. other causes of AKI in cirrhosis: What do serum or urine sodium clues, albumin challenges, and shifting diagnostic criteria actually reveal about getting the diagnosis right? 🔹 Sponsor : Oakstone CME Use the code "CORE25" for…
- #189 Bisphosphonates and Fracture Prevention Trial: Beyond Journal Club with NEJM Group
Who’s really at risk for fractures, and how should we be treating them? Most fragility fractures occur in patients without osteoporosis. Should we rethink who gets treated? And could just one or two IV infusions (spread years apart) of zol…
- #188 Orthostatic Hypotension Part 2: Gray Matters Segment
Medications for orthostatic hypotension! When to initiate treatment, how to use them safely, and what to do when new issues arise during treatment. How do those change if someone has autonomic failure? What do you do when your patient has…
- #187 Orthostatic Hypotension Part 1: Gray Matters Segment
Learn specific, practical ways to counsel patients on non-pharmacologic interventions. What is our goal with OH treatment? Is it the blood pressure number that matters? How do we avoid missing neurogenic causes of orthostatic hypotension (…
- #186 Pneumothorax: 5 Pearls Segment
Next time you’re squinting at a chest tube, feel confident you know exactly what to look for and why. Hear it explained in a way that really sticks! 🔹 Sponsor : Oakstone CME’s ACP MKSAP Audio Companion Use the code "CORE30" for 30% off ef…
- #185 Neutropenia: 5 Pearls Segment
How do you work up neutropenia? When is neutropenia benign? When do neutrophils recover? How can you diagnose neutropenic fever in the first 15 minutes and start antibiotics in the first 60 minutes? Do you always add MRSA coverages? Only P…
- #184 Stories for the Feels
Have a good laugh and reflect deeply with these three stories that hit the feels in different ways. If you'd love to hear more stories from Dr. Maria Rosasco, check out some of her other appearances on the podcast: July Stories and Handoff…
- #183 Diagnose the Clinician: Hoofbeats Segment
What went wrong? What were the reasoning or contextual missteps that led us astray? 🔹 Sponsor : NEJM Fellowship Program, click here to learn more and/or apply ! Due Aug 1, 2025 🔹 Transcript and Show Notes Timestamps: (00:02) | Case Prese…
- #182 Pleural Effusions: 5 Pearls Segment
Imaging Pearls | (01:12) Deciding on Thoracentesis | (04:00) Light’s Criteria and Pseudoexudates | (07:00) Pleural Fluid Studies: pH and Cell Differential | (16:56) Diagnosing and Treating Parapneumonic Effusions | (23:32) Malignant Pleura…
- #181 July Stories 3.0
Listen for some good laughs and relatable stories! In this episode, we share raw and real stories from July — from rapid responses to unexpected kindness — and reflect on the emotional weight of starting out in medicine. 🔹 Sponsor : NEJM…
- #180 Beta-Blockers & REDUCE-AMI Trial: Beyond Journal Club Segment with NEJM Group
How much do beta blockers help after a heart attack, even when the heart’s pumping well? In this episode, we revisit the origins of beta blockers in post-MI care , examine how evidence evolved, and explore the REDUCE-AMI trial , which ques…
- #179 Invasive Fungal Disease: 5 Pearls Segment
🔹 What is invasive fungal disease, and who is most at risk for developing invasive fungal disease? (~ 02:46) 🔹 What are the main classes of fungi? (~11:35) 🔹 What are the pros and cons of B-D Glucan and Galactomannan (~19:16) 🔹 How to…
- #178 Continuous Glucose Monitor (CGM): 5 Pearls Segment
🔹What are clinically relevant limitations of an A1c vs. a CGM (1:40) 🔹What do the different parts of the ambulatory glucose profile tell you? (09:59) 🔹What are common pitfalls, medications, lifestyle patterns that are important to ask y…
- #177 Interventional Radiology (IR) 101: 5 Pearls Segment
🔹When is an U/S vs. CT vs. MRI helpful before consulting Interventional Radiology? 🔹What factors go into an IR pre-op evaluation? 🔹 When do drains go in, and when do they come out? 🔹 When a patient has trouble with a drain, what are th…
- #176 Constipation Medications: 5 Pearls Segment
🔹 High-yield reversible causes of constipation? (02:26) 🔹 Which type of fiber is more helpful? And is more hydration really better? And bulk-forming laxatives (9:03) 🔹 Osmotic vs Stimulant Laxatives (15:06) 🔹 Suppositories and enemas?…
- #175 A Revolution in HIV Prevention & The PURPOSE Trials: Beyond Journal Club Segment with NEJM Group
How good are we at preventing HIV? How do efficacy and effectiveness differ? We journey from oral pre-exposure prophylaxis (PrEP) to long-acting injectables , and then to the PURPOSE trials , which look at the use of long-acting lenacapavi…
- #174 Lp(a) and ASCVD Risk: 5 Pearls Segment
What does Lipoprotein(a) tell us that a standard lipid panel doesn’t? Should we be testing everyone for it? Dive into the genetics, clinical implications, and evolving management strategies for Lp(a). Learn how to interpret results, counse…
- #173 Hypercoagulability Workup: 5 Pearls Segment
A new way to think of clots beyond provoked vs. unprovoked: Learn all about how important it is to think about reversibility! What patient states affect the inherited thrombophilia testing? Learn the nuances and practical approaches! 🔹 Sp…
- #172 Microplastics and Macro CV Health Problems: Beyond Journal Club on APACHe Study with NEJM Group
What is the impact of microplastics on human health? How can we use observational data to support the argument that microplastics may lead to poor health outcomes? Join us as we tackle these questions and discuss the APAChE study on microp…
- #171 Hospice Music Therapy: Bonus Episode
What is the last sense to go? How can music create connection, ease anxiety, and help process emotions at the end of life? Join Dr. Jafar Al-Mondhiry, Dr. Harry Han, and music therapist Bryanna Tobin as they explore the power of music ther…
- #170 ILD and High-Risk Medication Prescribing: Gray Matters Segment
Incidental fibrosis on CT —what now? What does prone imaging tell you? Is it fibrosis, aspiration, or atelectasis? And once you diagnose ILD, does the “alphabet soup” really matter for treatment? Antifibrotics vs. immunosuppression? Plus,…
- #169 MGUS to Multiple Myeloma Diagnostics and Counseling: 5 Pearls Segment
SPEP vs. UPEP? What does it tell you and not tell you? What is the role for immunofixation and free light chains in diagnosis? Learn about paraneoplastic antibodies with MGCS and its renal, neurologic, and dermatologic manifestations! Spon…
- #168 Immune Checkpoint Inhibitor Adverse Events 2.0: 5 Pearls Segment
How do you differentiate immune checkpoint inhibitor-related adverse events aka IrAEs from other conditions like infection? Join as we go through pneumonitis, colitis, dermatitis and endocrinopathies due to immune checkpoint inhibitor toxi…
- #167 Best of YouTube 2024: Anion Gap Metabolic Acidosis, Inhaler Use, Iron Deficiency in Pregnancy
YouTube Videos Anion Gap Metabolic Acidosis: https://youtu.be/oE0lygmMANM Inhaler Delivery Systems: https://youtu.be/yYPdjClm9Bg Iron Deficiency in Pregnancy https://youtu.be/xTzYSXUbLsc Subscribe to Core IM’s YouTube Channel for more behi…
- #166 Stress Ulcer Prophylaxis in the ICU and REVISE Trial: Beyond Journal Club with NEJM Group
What’s the evidence been for the use of PPIs in mechanically ventilated patients? What do more recent studies reveal about PPIs and possible harmful side effects of aspiration pneumonia and C. difficile colitis? To find out, tune into the…
- #165 Peripheral Arterial Disease: 5 Pearls Segment
Why are we missing peripheral arterial disease (PAD)? How is it diagnosed using the Ankle-Brachial Index (ABI)? What treatments improve symptoms and reduce cardiovascular risks? When should revascularization be considered? Transcript and S…
- #164 TPN/PPN Parenteral Nutrition: 5 Pearls Segment
How is TPN and PPN similar and how is it different? When should each be used? How does bacterial overgrowth lead to complications? Does TPN cause diarrhea? Transcript and Show notes Behind the Scenes Youtube Interview Subscribe to Core IM’…
- #163 Urine Drug Screening Nuances: 5 Pearls Segment
Limitations to urine drug screening (UDS) in primary care? What are common false positives and false negatives with the urine drug screen test? Transcript and Show notes Behind The Scenes YouTube Interviews Subscribe to Core IM’s YouTube C…
- #162 Hospice 102: Practical Tips and Nuances
What if a patient can't afford hospice? Which medications do you deprescribe when on hospice? What happens when patients who are on hospice return to the hospital or ED? Sponsor : Imagine leveraging A.I to do pre-charting before seeing a p…
- #161 Transfusion Thresholds and the MINT Trial: Beyond Journal Club with NEJM Group
Can the MINT trial change how we treat anemia in acute MI? The largest trial of its kind compared liberal vs. restrictive transfusion strategies in patients with myocardial infarction. Sponsor : Freed is an AI scribe that listens and write…
- #160 Moral Distress Part 2: At the Bedside Segment
Strategies to address moral distress and moral injury — hear from the experts on their work on the topic! Transcript and Show notes Subscribe to Core IM’s YouTube Channel for more behind the scenes, whiteboard animations and more! Timestam…
- #159 Moral Distress Part 1: At the Bedside Segment
What is moral residue vs. moral injury vs moral distress? How do these concepts impact us as clinicians? Sponsor : Whether you're looking to open your own practice or buy into a group , Panacea Financial understands the unique needs of phy…
- #158 Diuretics Resistance Cases
Listen to 3 cardiorenal cases that highlight that “without flow it really doesn't matter what you're doing with the diuretic!” Sponsor : Freed is an AI scribe that listens and writes your note in learns your style over time and is HIPAA co…