Fibrin polymerization and thrombosis; preventing CD19-negative relapse after CAR T-cell therapy in ALL; and impact of aberrant FUS condensates on HSC aging
This episode discusses fibrinogen polymerization's role in thrombosis, strategies for preventing CD19-negative relapse post-CAR T-cell therapy for acute lymphoblastic leukemia, and how increased FUS levels contribute to hematopoietic stem cell aging.